A Case Report of Localized Scleroderma Reported to the Dental Clinic with Literature Review

(Pages: 51-56)

Sridevi Ugrappa and Ajay Jain

Faculty of Dentistry, AIMST Dental Institute, AIMST University, Semeling 08100 Bedong, Kedah, Malaysia

DOI: https://doi.org/10.30576/2414-2050.2020.06.9



Abstract: Scleroderma (aka systemic sclerosis) is a rare multi-system autoimmune disorder which is characterized by the increased synthesis and deposition of the collagen in the connective tissue leading to the fibrosis of the skin and involved internal organ. Alteration indicates the activation and disturbances in the immune system by infiltration of auto-antibodies and perivascular lymphocytic cells causing to vascular disturbances and tissue hypoxia. These changes are manifested as atrophy of the skin and/or mucosa, subcutaneous tissue, muscles, and internal organs. Such changes can be classified into two types, namely, morphea (localized) and diffuse (systemic). The present case report discusses about oral involvement in patient affected by scleroderma with a short review of literature.

Keywords: Autoimmune disorder, oral medicine localized scleroderma, pathogenesis, systemic sclerosis.