Improvements in Obstructive Sleep Apnea Syndrome (OSAs) in Patient with Treacher Collins Syndrome (TCs): A Multidisciplinary Approach

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A.P. Cazzolla1, F. Riccitiello2, D. Ciavarella3, M. Laurenziello3, L. Lo Muzio3, G.F. Favia1, N.F. Testa1 and M.G. Lacaita1

1Clinic of Dentistry, University of Bari, Bari, Italy; 2Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples “Federico II”-Naples, Italy and 3Department of Clinical and Experimental Medicine, School of Dentistry, University of Foggia, Foggia, Italy




Abstract: Aims

Introduction: The aim of this work is to present the improvements of a proper management of OSAs in a patient with TCs through a multidisciplinary approach with Oral-Maxillofacial team.

Obstructive Sleep Apnea syndrome (OSAs) is characterized by upper airway obstruction during sleep and an increase airflow resistance mainly at the level of oropharynx, resulting in reduced pulmonary ventilation and hypoxia.

Results and Discussion: Computed tomography shows an improvement in axial and sagittal section of the Minimal Cross Sectional Areas of the pharyngeal airway. The Cephalometric analysis showed an increased of SNA, MP-H, Go-Gn/H and a decrease of SNB, ANB, PAS, AHI.

The different modifications of the LeFort I osteotomy have been proved to diminish the nasal airway resistance.

Conclusions: Five years after surgery, the patient has a stable clinical result with a good aesthetic and a harmonious facial balance. He does not suffer from snoring, daytime somnolence or fatigue and has not required the use of c-PAP since surgery.

Keywords: Treacher Collins syndrome, Obstructive sleep apnea syndrome, Cephalometry, AHI, Surgical management.